◘ Skin Anti-Aging
◘ Skin Free Radical Damage
◘ Skin Sun Damage
◘ Premature Skin Aging
◘ Skin Anti-Aging Products
◘ Anti-Aging Diet
Skin & Vitamin A
As explained in the Anti-Aging section, malfunction at the cellular level becomes collective as we age which leads to progressive malfunction of the skin as an organ. In time the skinís microvascular system begins to break down due to blockage, breaks, leaks, etc. The loss of small feeder vessels has major impact in escalating the skinís aging process because the skin receives less nutrients, proteins, amino acids, essential fatty acids, protective antioxidants, oxygen and so on. This reduces the cellsí ability to function and subsequently the skinís ability to perform its various maintenance, protective, immune and reparative processes. To achieve visible rejuvenation benefits, attention must be given to rebuilding the skin's microvascular system so the skin may function in a more youthful and healthier manner again.
Angiogenesis is the medical term for the bodyís ability to rebuild its vascular system and within the skin this process is stimulated whenever the skin is bruised, cut or incurs damage to its vascular system. The major biochemicals that stimulate the rebuilding of the vascular system are angiogenesis factor (AF) and vascular endothelial growth factor (VEGF) and these chemicals are produced in the skin as a natural result of injury. The presence of blood spilled into the skin stimulates the production of AF and VEGF.
Vitamin A in its most active forms is highly involved in the process of repairing and rejuvenating the skin. It is able to attach to receptors on macrophage cells (specialized skin cells involved in immune and repair functions). Macrophage cells then produce the chemicals AF and VEGF, stimulating enhancement of the skinís microvascular system. Volumes of research have been published on the actions of vitamin A within the skin. In one study an 89% increase of the microvascular system was achieved after six months of daily vitamin A application. Twelve months after discontinuing the vitamin A treatments 23% of the beneficial effects still remained. The benefits of vitamin A can be seen in the improved healthful appearance of the skin and its color and they reflect the skin's improved health.
An initial strategy in skin rejuvenation should be improving the vascular integrity of the skin because this will allow the skin as an organ (and cell by cell) to react more effectively to other forms of rejuvenation stimulation. In short, the skin must have the materials and the energy and oxygen to perform the desired processes. If the skin has restrictions on its capacity, then the results of repair stimulation will be equally as restricted.
Like Retin-Aģ, some people may not be able to tolerate the use of Vitamin A / Antioxidant Complex on a daily basis and may need to use the product every other day or every third day. People who must limit the use of this product will still get excellent benefits because their skin is highly sensitive to active vitamin A. Typically, people with a light complexion and dry skin may be more sensitive than darker or oilier skin types.
Research done by Fisher et al in 1998 at the University of Michigan Medical School suggests that higher levels of vitamin A within the skin may prove to have therapeutic and anti-aging value immediately following UV (sun) exposure. Vitamin A stimulates the removal and replacement of damaged skin components. In the past it was incorrectly thought that the use of topical vitamin A products made the skin more sensitive to sun damage. This is incorrect and topical vitamin A has reparative benefits. Because topical vitamin A tends to promote exfoliation of outer cells, it can result in less protective skin density for skin that is not properly treated with sun protection.
© 2006 Apresia / Skintactix